Objective To discuss the change and significance of heart rate variability(HRV) before and after transcatheter closure in patients with atrial septal defect(ASD).

• 目的通过观察房间隔缺损(ASD)介入封堵术前后心率变异性(HRV)的变化,探讨介入封堵术对ASD患者心率变异性的影响及其意义。