Objective To observe the changes of the renocortical tissue lipid peroxicition of acute renal failure induced by diffent dose cisplatin in rats and to study the mechanism of cisplatin nephrotoxicity.

• 目的观察不同剂量顺铂致大鼠急性肾衰时肾皮质脂质过氧化的变化,探讨顺铂肾毒性的发生机制。