Objective To observe whether local aldosterone (ALDO) may be synthesized by hum an renal proximal tubular cell lines (HKC) and investigate whether endothelin-1 (ET-1) has effects on the production of local ALDO.

• 目的 观察人近端肾小管上皮细胞能否合成组织醛固酮(ALDO),以及内皮素-1 (ET-1)对该作用的影响。