Objective: To construct an eukaryotic co-expression recombinant containing mouse interleukin 21(IL-21) and tuberculosis antigen 85A(Ag85A), it provides the new strategy for further development of new type anti-tuberculosis DNA vaccines.

• 目的:利用真核表达质粒pRSC,构建结核杆菌抗原85A(Ag85A)与小鼠白细胞介素21(mIL21)共表达重组体pRSC-mIL21-Ag85A,为研究新型结核杆菌DNA疫苗提供新的策略。