Objective: To develop a simultaneous assay for desciclovir (DCV) and acyclovir (ACV) in blood by reverse-phase high performance liquid chromatography (HPLC) in order to support pharmacokinetic studies and blood concentration monitoring in the dog.

• 目的：为了满足地苷洛韦（脱氧无环鸟苷，DCV）药代动力学研究和血药浓度监测的需要，建立了能够同时测定血中DCV和阿苷洛韦（无环鸟苷，ACV）的反相高效液相色谱（HPLC）分离测定方法。