Objective:To observe the effect of higher dosage of clozapine on ECG in QT dispersion (QTd) and post regulating QT dispersion (QTcd), explore the possible mechanism and prevention of sudden death during clozapine treatment.

• 目的 : 探讨较大剂量氯氮平对心电图QT离散度 (QTd)及校正后的QT离散度 (QTcd)的影响 ,从而探讨其可能引起猝死的机制及预防方法。