Objective. Simulate the reduced glycosaminoglycan content and altered mechanics observed in intervertebral disc degeneration using a controlled injection of chondroitinase ABC (ChABC).

• 目的：模拟氨基葡聚糖含量减少模型以及通过适当的软骨素酶ABC注射液来观察椎间盘退变发生气制。