One of transcription factors, PIF3, has been isolated from Arabidopsis, and verified to interact with phytochrome by yeast two-hybrid assay.

• 最近该领域又取得重大突破性进展，人们通过酵母双杂交技术克隆到在体内与光敏色素相互作用的转录因子，并证实被光活化的光敏色素直接进入细胞核与转录因子结合启动基因表达。