PKC inhibitor (H 7 and Stauroporine )could inhibit VSMC proliferation induced by Hcy with reduction of 3 H TdR incorporraion by 50% and 56% ,respectively.

• 结果Hcy可显著刺激平滑肌细胞增殖，10－4mol/LHcy使VSMC3H?TdR掺入较对照组增加1.；8倍。