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- Keywords Rat;Pachyntic ventricular myocyte;Calcium paradox;Calcium tolerant;Patch clamp.; 大鼠;肥厚心肌细胞;钙反常;耐钙;膜片钳;
- Pachyntic ventricular myocyte 肥厚心肌细胞
- ABSTRACT:Objective To investigate the method of stably isolating pachyntic Spraque Dawley rat calcium tolerant ventricular myocytes for patch clamp techniques. 随着心肌细胞电生理和分子生物学研究的兴起,成熟单个心肌细胞越来越多的应用于心血管疾病病理生理的研究。
- Method Ion currents of rabbit ventricular myocyte were recorded using the whole cell patch clamp technique. 方法应用全细胞膜片钳技术记录兔心室肌单个细胞的电流。
- Conclusions Inhibition of central sympathetic tone by clonidine can increase single ventricular myocyte contractile amplitude and improve heart function in aged rats. 结论 抑制中枢交感神经紧张性可改善老年大鼠心功能,增加心肌细胞的收缩幅度。
- The characters of ClC-2 chloride channel in rat ventricular myocytes. 大白鼠心室肌细胞ClC-2型氯通道的特性
- ATP-Sensitive Potassium Current Alterations during Ischemic Preconditioning in Guinea Pig Ventricular Myocytes. 心肌缺血预适应引起的ATP敏感性钾电流变化。
- To study the effect of agmatine (Agm) on L-type calcium current (ICa-L) in rat ventricular myocytes. 目的:观察胍丁胺(Agm)对大鼠心室肌细胞L-型钙通道电流(I_(Ca-L))的影响.
- Stored in ventricular myocytes, it is released during ventricular stretch and increased transmural pressure. 由于其储存在心室的心肌细胞,因此当心室舒张期及跨壁压增高时才释放。
- Mechanisms of cyclovirobuxine D on APD prolongation in rat ventricular myocytes. 海马干细胞分化的神经元电生理特征的初步探讨。
- Conclusions Ketamine inhihites the L-type calcium channels of ventricular myocytes in a good dose-response manner. 结论氯胺酮对心肌细胞膜L-型钙通道具有抑制作用,其抑制程度有浓度依赖性。
- Brain natriuretic peptide,a peptide hormone secreted chiefly by ventricular myocytes,plays a key role in body fluid equilibrium. 脑钠素是一种主要由心室肌细胞分泌的肽类激素,在体液平衡的调节中发挥关键作用。
- Methods Whole cell patch-clamp technique was used to observe potassium currents in enzymatically isolated ventricular myocytes of rat or guinea-pig. 方法用酶解法分离单个心室肌细胞,并用全细胞膜片钳记录技术。
- Effects of Bepridil on Action Potential Duration and Main Ion Currents Involved in the Depolarization and Repolarization of Isolated Guinea Pig Ventricular Myocytes. Bepridil对豚鼠心室肌细胞动作电位时程和跨膜离子流的作用。
- The electrophysiological effect of CGRP on rabbit ventricular myocytes in vitro (under normal, ischemia and with CsCl perfusion condition) have been studied. 3. 2. CGRP对在体和离休家兔心肌在正常及缺血条件下均有明显加速复极的作用。
- Positive Inotropic Effect of Endothelin-1 in Ventricular Myocyte of Rats 内皮素-1对大鼠心肌细胞正性肌力作用的研究
- Keywords phenylarsine oxide;L-type Ca 2+ current;ventricular myocyte; 氧化苯胂;钙电流;心室肌细胞;
- The anion currents elicited by swelling rat ventricular myocytes in 1T and 0.6T solution, namely ICl,swell were studied using patch clamp techniques with whole - cell voltage clamp configuration. 采用全细胞电压钳方式记录大鼠心室肌细胞在1T及0.;6T溶液中ICl;swell的变化。
- AIM: To investigate the changes of the L-type calcium channel subunit expression and calcium currents (I_~Ca -L) in cultured rat ventricular myocytes infected by coxsackie virus B_3 (CVB_3). 目的研究大鼠心室肌细胞感染柯萨奇病毒B3(CVB3)后L型钙通道mRNA表达量及其电生理特性的变化。
- Abstract Using glass microelectrode technique and whole-cell patch clamp technique, we studied the action and mech-anism of endothelin-l (ET-1)inducing early after depolarizations(EADs) in guinea pig ventricular myocytes. 应用玻璃微电极技术和膜片钳全细胞记录,研究了内皮素(ET-1)致豚鼠心室肌细胞早期后除极(EADs)的作用及发生机制。