Pharmacologic infusion of activated protein C (APC) improves survival in severe sepsis, and platelet factor 4 (PF4) accelerates APC generation in a primate thrombin-infusion model.

• APC的药理性输注可以提高严重的脓毒血症的存活率，血小板4因子（PF4）加速了灵长动物凝血酶输注模型中APC的产生。