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- It is useful for discovery of novel fungal polyketide synthase gene clusters. 本文综述了近五年来建立的几种分离真菌聚酮合酶基因的方法。
- biosynthesis Polyketide synthase 聚酮合酶
- Keywords Polyketide;Polyketide synthase;Combinatorial biosynthesis; 聚酮化合物;聚酮合酶;组合生物合成;
- Polyketide synthases catalyze the synthesis of complex natural products including macrolide antibiotics from simple precursors such as propionyl-CoA and methylmalonyl-CoA. 聚酮合成酶能够合成包括许多大环内酯类抗生素在内的聚酮类天然产物,它的结构和功能的模块性为组合生物合成的产生和发展奠定了基础。
- Keywords Streptomyces avermitilis,avermectins B1,ivermectins,oligomycin,polyketide synthase; 阿维链霉菌;阿维菌素B1;伊维菌素;寡霉素;聚酮合酶;
- Keywords polyketide;combinatorial biosynthesis;polyketide synthase;microbial medicine;gene cluster; 聚酮类;组合生物合成;聚酮合酶;微生物药物;基因簇;
- Keywords Polyketide synthase;Substrate specificity;Combinatorial biosynthesis;Acyltransferase; 聚酮合成酶;底物专一性;组合生物合成;酰基转移酶;
- Keywords Polyketide synthase （PKS）;Aromatic polyketide;Polymerase chain reaction （PCR）;Extreme environment;Molecular screening;Actinomycetes; 聚酮合酶;芳香环聚酮类化合物;聚合酶链反应;极端环境;分子筛选放线菌;
- Keywords polyketide synthase（PKS）,PKS-specific antibodies,heterologous expression,antifungal antibiotic,bi-functional expression vector; 聚酮合酶（PKS）;PKS特异性抗体;异源表达;抗真菌抗生素;双功能表达载体;
- Polyketide synthase 聚酮合酶
- polyketide synthase gene 聚酮合酶基因
- Synthase polymorphism has become a focus of study. 合酶基因多态性已成为研究的热点。
- polyketide synthases 聚酮合成酶
- Polyketide synthases (PKS) 多聚酮合成酶（PKS）
- Effect of iodine on the activity of nitric oxide synthase in rat hippocampus. 高碘对大鼠海马一氧化氮合酶蛋白表达的影响。
- Chitin synthase is the important enzyme that converts UDP-GlcNAc to chitin. 摘要几丁质合成酶是生物合成几丁质的关键物质。
- ATP is produced by a complex in the mitochondrial membrane called ATP synthase. 三磷酸腺苷是由一个复杂的线粒体膜称为ATP合酶。
- The gradient this creates produces ATP by a similar ATP synthase complex. 这造成的梯度产生ATP的一个类似的ATP合酶复杂。
- Allele oxide synthase (AOS) was a key enzyme in JA biosynthesis pathway. 丙二烯氧化物合成酶基因（allele oxide sysnthase，AOS）是JA生物合成的关键酶基因，也是影响JA信号途径的调控基因。
- Chitin synthase is the important enzyme that convert UDP-GlcNAc to chitin. 几丁质合成酶是生物合成几丁质的关键物质。
