Preious studies hae shown that a reduction in insulin-like signaling in the neurons extends the lifespan in the worm, Caenorhabditis elegans, and the fruit fly, Drosophila melanogaster.

• 之前已经有研究证实，减少神经元中胰岛素样信号可以延长蠕虫、新杆状线虫、果蝇及黑腹果蝇的寿命。