Previous studies have identified CYP1 A2 and CYP3A4 as the major enzymes for AFB_1 activation in human liver.

• 但由于CYP1A2主要在肝脏中表达，而在肺脏中甚微，因而至今还不清楚在人肺脏中究竟哪些CYPs在AFB1的代谢活化中发挥关键性的作用。