Progressive arterial hypoxemia, despite an increased fraction of inspired oxygen (FIO2) by mask, cannual, or endotracheal tube, is a hallmark of ARDS. This development is called refractory hypoxemia.

  • 使用面罩、导管或气管内插管增加吸入氧气分数(FIO2)后仍出现进行性动脉血氧低,此为ARDS标志性证据,为难治性低氧血症期。
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