您要查找的是不是：
- Proteasome inhihitor 蛋白酶体抑制剂
- The proteasome then digests it into its constituent amino acids. 蛋白分解体就会将这个有标示的蛋白质，分解成各种胺基酸。
- Polyubiquinated proteins are eventually degraded by the 26S proteasome. 泛素化的蛋白通常通过26S蛋白酶体进行降解。
- They alert the nerve cell's proteasome, a garbage disposal system, to the existence of the bedecked protein. 泛素链会将有这种标识的蛋白质通报给神经元的蛋白分解体（垃圾清理系统）。
- Objectives:To compare the effect of defferent routes of nutritional support on the 26 S proteasome. 目的:通过动物实验为烧伤病人的营养支持提供必要的理论依据。
- Some progress has been achieved in this field and recent development of proteasome inhibitors are reviewed. 在此对蛋白酶体的结构、功能及其抑制剂的研究进展进行综述。
- The product of proto oncogene c Cbl has been proved as a new ubiquitin ligase (E3) of RING finger type for ubiquitin proteasome pathway. c Cbl最近被证明是泛素 蛋白酶体 (ubiquitin proteasome)通路中的一个新的RINGFinger型泛素连接酶 (ubiquitinligase ;E3) .
- The proteasome is primarily responsible for intracellular protein degradation.The abnormality of its activity is sign of tumorigenesis. 蛋白酶体负责细胞内蛋白的降解，其活性的异常改变是肿瘤发生的标志。
- In addition, following chemotherapy, there was a significant decrease in proteasome leels in patients who responded compared to those who did not. 此外，对化疗有反应的患者在治疗后蛋白酶体水平有显著的降低。
- Objective To explore the role of proteasome inhibitor 3,4-dichloroisocoumarin(DCI) on apoptosis of human gastric cancer cell line BGC823. 目的:探讨蛋白酶体抑制剂3,4-二氯异香豆素(DCI)对人胃癌细胞系BGC823体外增殖和凋亡的影响。
- The expression of MHC I molecules on the muscle cells can be inhibited by the proteasome inhibitors lactacystin and MG132. 用蛋白酶体抑制剂抑制可以明显阻断肌细胞MHC I分子的表达；
- Furthermore,the effect of proteasome inhibitors and TAP on particle antigens cross presentation was investigated by FACS analysis. 进而,采用流式细胞技术研究了不同蛋白酶体抑制剂以及TAP对噬菌体颗粒抗原交叉呈递的影响。
- AIM: To investigate the effect of proteasome inhibitor MG132 on the proliferation and apoptosis of dopaminergic PC12 cells. 蛋白酶体抑制剂；PC12细胞；帕金森病；
- This paper reviews the biological functions of proteasome in signal trans duc tion and its potential roles in neurodegenerative diseases. 本文综述蛋白酶体在细胞信号转导 中的生物学功能和在神经退行性疾病中的可能作用。
- Then she added an antibody that cleared the cells of prions but left the ubiquitins, the proteasome and the waste proteins in place. 然后她又向细胞注射了可清除朊病毒而不伤及降解酶和水解酶与废物的抗体。
- The ubiquitin/26S proteosome pathway mainly consists of ubiquitin activating enzyme (E1), ubiquitin conjugating enzyme (E2), ubiquitin protein ligase (E3), and 26S proteasome. 摘要泛素蛋白酶体途径主要由泛素活化酶、泛素结合酶、泛素蛋白连接酶和26S蛋白酶体组成。
- The recent progress of boronic acid derivatives used as enzyme inhibitors is reviewed focused on the serine protease inhibitors, proteasome inhibitors, and arginase inhibitors. 综述了有机硼酸类化合物作为酶抑制剂的研究进展,重点介绍了近年来发现的丝氨酸蛋白酶抑制剂、蛋白酶体抑制剂和精氨酸酶抑制剂。
- Bortezomib is a new proteasome inhibitor.Clinical studies demonstrat that bortezomib plays role in the treatment for relapsed, refractory and initially treated multiple myeloma. 硼替佐米作为一种新型的蛋白酶体抑制剂,临床上可用于治疗复发性、难治性或初治的多发性骨髓瘤。
- Cancer-causing mutations can also activate the proteasome, so drugs that block protein breakdown, such as nelfinavir, could theoretically halt both diseases. 变异的癌症细胞也可以激活蛋白酶体，像那非那韦之类阻断蛋白分解的药物，理论上可以治疗癌症。
- The proteasome is composed of three protein subcomplexes: a central, cylindrical complex, the 20S proteasome, is capped at either end by a copy of the 19S ATPase complex. 最简单的蛋白酶体是在古生物中发现的。
