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- Protein tyrosine kinases play an important role in signal transduction pathways in regulating a number of cellular functions. 蛋白质酪氨酸在一系列细胞活动的信号转导途径中起着重要的作用。
- protein tyrosine kinases inhibitor 酪氨酸激酶抑制剂
- Janus protein tyrosin kinases 1 (JAK1) JAK1
- receptor protein tyrosine kinases 受体蛋白质酪氨酸激酶
- OBJECTIVE:To discuss the progress and the clinical application evaluation of protein tyrosine kinase(PTK) inhibitors. 目的:探讨酪氨酸激酶抑制剂的进展与临床应用评价。
- Keywords liver regeneration;protein tyrosine kinases; 肝再生;蛋白质酪氨酸激酶;
- Objective To approach the mechanism of action of anticancer and the investigation progress of protein tyrosine kinase (PTK). 摘要目的探讨蛋白酪氨酸激酶抑制剂抗肿瘤作用机理及其研究进展。
- Objective To approach the mechanism of action of anticancer and the investigation progress of protein tyrosine kinase(PTK). 目的探讨蛋白酪氨酸激酶抑制剂抗肿瘤作用机理及其研究进展。
- Receptor tyrosine kinase (RTK), a membrane receptor superfamily with intrinsic protein tyrosine kinase activity, has many members and complicated signal transduction pathways. 摘要受体酪氨酸激酶是一个具有内在酪氨酸蛋白激酶活性的膜受体超家族,成员众多,信号转导通路复杂多样。
- DDR2 is a newly identified receptor protein tyrosine kinase, which is composed of three parts: DR region on the N terminus, a long justatransmembrane region (JM) between DR region and transmembrane region, and intracellular region in cytoplasma. DDR2是一类新发现的受体型蛋白酪氨酸激酶,其分子结构由三部分组成:一是N端的DR区,二是在DR与跨膜区之间的很长的邻跨膜区(justatransmembrane region,JM),三是在胞浆内的胞内区。
- ABSTRACT STI571 is one of the target drugs to Bcr/Abl oncoprotein.It is a special inhibitor to the activation of protein tyrosine kinase by interrupting phosphorylation of substrate. 摘 要 STI571 是一种针对Bcr/Abl基因表达产物的靶向治疗药物,可以阻止底物的酪氨酸残基磷酸化,发挥特异性酪氨酸蛋白激酶活性抑制作用,临床研究结果证明对慢性粒细胞白血病的疗效显著优于干扰素及其它化疗药物。
- HTS model for protein tyrosine kinase inhibitors 酪氨酸蛋白激酶抑制剂的高通量筛选模型
- Keywords Cholesteatoma Middle ear Protein tyrosine kinases Epidermal Growth Factor Receptor(EGFR)Phosphotyrosine Immunohistochemistry.; 关键词胆脂瘤;中耳;酪氨酸蛋白激酶;表皮生长因子受体;磷酸化酪氨酸;免疫组织化学;
- Lymphocyte-specific protein tyrosine kinase 淋巴细胞特异性酪氨酸蛋白激酶
- protein tyrosine kinase inhibitor 酪氨酸蛋白激酶抑制剂
- non-receptor protein tyrosine kinase 非受体酪氨酸激酶
- Roles of receptor tyrosine kinases, integrins, and Shc. 外文期刊 Mechanotransduction in response to shear stress.
- receptor protein tyrosine kinase RPTK
- Tyrosine kinases are involved in the pathogenesis of most cancers. 酪氨酸激酶参与了大部分肿瘤的发病。