Puzzledom in developing mineral resources,advantages and application status of microbial metallurgy are elaborated.Research status and direction of biotechnology in hydrometallurgy is discussed.

• 阐述了矿产资源开发领域的困境、微生物冶金技术的优点和应用现状,介绍了生物技术在湿法冶金领域的研究状况和研究趋势。