Recommendation 15(Other factors): When adjusting therapy , factors apart from disease activity, such as progression of structural damage, co-morbidities and safety issues should be taken into account.

• 建议15(其他因素):在调整治疗时，除考虑疾病活动因素外，还应考虑其他因素如关节结构破坏、并发疾病和安全性方面。