Regulated by the core promoter, transcription of this DNA produces pregenomic and precore messenger RNAs (mRNAs), from which hepatitis Be/c (Hbe/c) antigens and polymerase proteins are translated.

• 经核心启动子引导，基因转录出前基因mRNA和前C mRNA，并翻译出HBe/c Ag和聚合酶。