Remarkably,the enzyme activity of CYP1A2 was induced by Glycyrrhiza alone,and inhibited by Euphorbia pekinensis,Euphorbia kansui,and Daphne genkwa whether or not in combination with Glycyrrhiza.

• 单用甘草诱导CYP1A2的酶活性; 大戟、甘遂、芫花单用抑制CYP1A2的酶活性;