Resluts By oral administration with HS 2, the capacity of learning and memory of the AD model mice was improved. HS 2 can downregulate the expression of PS1, BACE and decrease the amount of senile plaque in their brains.

• 结果 低、中、高剂量的HS2 均能改善AD小鼠学习记忆 ,下调PS1和BACE基因的表达 ,减少老年斑的生成。