Results The HSV TK vector producer cell line GRC 1/TK was obtained which confered a chemosensitivity to ACV. Conclusions HSV1 TK gene might be used in gene therapy of human renal cancer GRC 1 cells.

• 结论 HSV1 TK基因可成功转染人肾癌GRC 1细胞 ,为基因治疗肾癌提供实验依据。