Results We isolated, in the absence of a known stimulating antigen, a autoreactive CD4 + T cell line(ATL) and two T cell clones from BXSB mice. TCR TRBV2S1, TRAV5S1 and TRAV10S1 were used in ATL.

• T细胞系主要应用TRBV2S1、TRAV5S1和TRAV10S1,而 2个T细胞克隆均为TRBV2S1和TRAV10S1。