Reverse phase high-performance liquid chromatography(RP-HPLC) was applied to determine the S-adenosyl-l-methionine(SAM) in erythromycin fermentation course.

• 建立用反相高效液相色谱(RP-HPLC)检测红霉素发酵液中S-腺苷甲硫氨酸(SAM)的方法,观察其在发酵过程中的变化。