SD rats were maintained under a cyclic light/dark environment for 7 days and then kept in darkness for 36 hours before experiment. The rats were sacrificed after continuous intense white light exposure for 3,6,9,12,15,and 18 hours.

• 所有sd大鼠经循环光环境适应7d,实验前暗适应36h,分别于光照3,6,9,12,15和18h,灌流固定,摘除眼球。