SIV/SHIV macaque model has been widely used in AIDS research.However, there are some limitations inherent in the current models that use either macaque animals or viruses.

• 目前在国际上SIV或SHIV感染的猕猴模型为最常用的AIDS研究模型，受猕猴背景及病毒特性等多种因素的影响，使得以上两种模型在HIV疫苗研究中仍存在一定的局限性。