Serum alamine aminotransferase (ALT), hyaluronic acid (HA), hydroxyproline (HyP) in liver tissue and pathological change were observed in soluent compase group, tetrachloromethone group and (matrine group) rats for 3, 6, 12 wk.

• 观察3,6 ,12wk时溶剂对照组、四氯化碳组、苦参碱组血清丙氨酸转氨酶 (ALT)、透明质酸 (HA)、肝组织羟脯氨酸 (HyP)含量以及肝脏病理变化。