Seven adult healthy Pekingese weighed about 5kg were used as experimental animals. Liver lesion in dogs was induced by injecting the mixture of 60% carbon tetrachloride and 40% peanut oil subcutaneously per ten days for seventy days.

• 本试验采用前后对照的方法,选用5kg左右的健康成年北京犬7只,皮下分点注射含60%25四氯化碳的花生油乳剂,以诱发犬的实验性肝损伤,每10天注射1次。