Some drugs accumulate, producing higher concentratio in cells than in ECF, most commonly because they bind with protein, pho holipids, or nucleic acids.

• 某些药物在细胞内积聚，使细胞内浓度高于细胞外液浓度，最常见的原因是他们与蛋白质、磷脂或核酸的结合。