Tankyrase, a new telomeric poly (ADP ribose) polymerase (PARP), acts as a positive regulator of telomere elongation. It can influence chromosomal stability and is closely related to cell senescence, death and carcinogenesis.

• 端锚聚合酶 (tankyrase)是一种位于端粒的聚腺苷二磷酸核糖聚合酶 ,它在端粒酶阳性细胞中过表达可使端粒长度增加 ,从而影响染色体的稳定性 ,与细胞的衰老、死亡和癌变密切相关 ;