Telomere length is regulated by telomere binding protein, telomere cap protein, DNA duplicase and telomerase.Telomerase plays the most important role in maintaining telomere length.

• 影响端粒长度的因素包括：端粒结合蛋白、端粒帽蛋白、端粒酶及DNA复制酶等，其中端粒酶是最主要的因素。