The 14-3-3 proteins are a family of widely expressed acidic polypeptides in all eucaryotic cells, which act mainly as either homodimers or heterodimers.

• 14-3-3是一个在真核生物中广泛表达的酸性蛋白家族，主要以同源/异源二聚体形式存在，通过磷酸化丝/苏氨酸作用与靶蛋白或靶蛋白的2个结构域结合。