The AML1?ETO fusion proteins generated by chromosome translocation of t (8; 21) lead frequently to pathogenesis of acute myeloid leukemia (AML).
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- t(8;21)染色体易位是导致急性髓系白血病的最常见的发病机制；AML1 ETO是t(8;21)易位所产生的融合基因.
