The OmpL1 gene of Leptospira(L.) serovar lai was amplified and sequenced, and its nucleotide sequence, protein secondary structure and restriction endonuclease map were further analysed.

• 用PCR方法扩增不同毒力赖型钩体OmpL1基因片段，进行序列测定，用相关软件比较分析核苷酸序列、蛋白质二级结构以及限制性内切酶谱。