The activation of PTK/transcription activator signaling cascades can stimulate the excessive proliferation of mesangial cell proliferation and then result in diabetic nephropathy.

• 蛋白酪氨酸激酶/转录激活子途径信号级联放大的激活刺激肾小球膜细胞过度增殖，导致糖尿病肾病。