The aims of this study were not only to elucidate the relationship between drug resistance of MCF-7/ADR to ADR and GST- or DNA TopoII, but also to investigate the mechanism through which CEP reverses drug resistance.

• 通过上述实验来阐明MCF一7/ADR对ADR产生耐药性与GST一:、DNA Topo11之间的关系及CEP逆转耐药性的机理。