The breast cancer cells of MDA-MB-231 were orthotopically implanted in the five-week-old BALB/c female nude mice(class SPF)to establish the animal model.

• 在5周龄雌性、无特定病原体(SPF级)BALB/c裸小鼠原位接种人乳腺癌细胞(MDA-MB-231)制作动物模型。