The brown products of positive expression of C fos gene were abundant in lamina propia and muscularis in the aganglionic colon and were absent in the proximal dilated segment and normal colon.

• C fos蛋白免疫组化巨结肠无神经节细胞的痉挛段粘膜固有层和粘膜肌层中出现大量的棕褐色C fos蛋白表达产物 ,而巨结肠近段的扩张段未见C fos蛋白表达阳性产物。