The changes of PGE2 level and the effect of indomethacin on boas resorption stimulated by interlenkinl (IL-1) were studied in cultured neonatal rat calvariae. The method of radioimmunoa~y (RIA) was performed in this experimental study.

• 利用新生纯系KM小鼠颅盖骨体外培养模型，通过放免法检测培养液中PGE2含量的变化，研究白细胞介素一1（IL-1）刺激和介导骨吸收效应中PGE2的作用和相互关系以及消炎痛对此效应的作用。