The critical technology in producing ODTs is the technology to make them disintegrate rapidly. Lyophilization or freeze-drying, direct compression and compression after wet granulation are currently applied home and abroad.
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美
- 冷冻干燥压片将主药和辅料定量分装在一定模具中,冻干去水,制得高孔隙率的固体制剂,其质地疏松,崩解时限一般在15秒内。