The degree of suppression can be estimated by the time required to recover normal HPA responsiveness.Two studies have addressed this issue in patients treated with chronic corticosteroid therapy.

• 抑制程度可通过测定恢复正常下丘脑-垂体-肾上腺反应性所需的时间来估计，对两项长期用皮质类固醇治疗患者的研究已提出了这个问题。