The drawback of this type of prosthetic heart valve is the limited lifespan, on average from 5 to 10 years (but sometimes shorter) because of wear and calcification.

• 此种生物瓣膜临床应用时病人平均寿命受限，一般为5-10年（也有可能更短），是由于瓣膜的磨损和钙化所致。