The dynamic change of [Ca2+]i in single pancreatic acinar cell was determined by laser scanning confocal microscopy.

• 在无钙且含EGTA的培养液中LPS引起胰腺腺泡细胞[Ca~(2+)]_i缓慢、微弱的升高，而再次恢复培养液中Ca~(2+)至生理浓度，LPS可以引发一个快速、幅度更高而持久的[Ca~(2+)]_i变化；