The formation rate of metabolites for S (-) OFLX was faster than that for R (+) OFLX. There were significant differences between two enantiomers for their Vmax,Km and Clint.
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美
- S-(- )-OFLX代谢物的生成量和生成速度均大于R-(+ )-OFLX,两对映体的酶动力学参数也有显著差异。