The frequency of mdm- 2 gene amplification was higher in metastasis lymphnodus (57.1% ) than that in primary carcinoma foci(37.5% ). The mdm- 2 amplification was detected in 3 specimens of lymph micro- metastasis foci.

• mdm- 2在转移淋巴结中的扩增频率（ 12/21， 57.；1%25）高于胃原发癌灶（ 12/32， 37