The high-performance liquid chromatography (HPLC) method was developed to determine the effects of ultramicro-pulverization on the geniposide and berberine dissolubility of Huanglianjiedusan (HLJDS).

• 摘要应用高效液相色谱法(HPLC)比较了普通粉碎和超微粉碎对黄连解毒散中主要有效成分栀子苷和小檗碱溶出量的影响。