The inhibitory effect of the extract from SGY on contractility of isolated rat colonic smooth muscle strips may be associated with blocking VDC,ROC and SOC to prevent the calcium influx as well as to prevent the release of intracellular calcium.

• 疏肝饮具有抑制大鼠结肠平滑肌收缩的作用,机制可能涉及通过阻断电压门控钙通道(VDC)、受体操纵性钙通道(ROC)和钙库调控性钙通道(SOC)抑制胞外Ca2+内流,同时涉及抑制胞内Ca2+的释放。