The interleukin-2 mRNA is a labile transcript containing AU-rich elements(ARE) that is transiently stabilized by CD28 receptor signaling.

• CD28所诱导的白细胞介素（IL-2）的转录后调控被认为是与IL-2 mRNA 3’UTR区的富集腺嘌呤尿嘧啶保守区域（AU-rich elements，AREs）相关的。