The length of telomeres gradually decreases with increasing age and cell division number,which can lead to chromosome instability,so the changes in telomere length are closely linked to cell aging.

• 端粒的长度随着年龄和细胞分裂次数的增加而逐渐变短,因而导致染色体不稳定,因此端粒长度的变化与细胞衰老密切相关。